|
|
vitamin_K + H2O + a_protein_with_a_disulfide_bond <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + a_protein_with_reduced_L-cysteine_residues
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
M
|
|
BRENDA:
BR29366
MetaCyc:
1.1.4.1-RXN
|
|
|
|
vitamin_K + O2 + reduced_acceptor <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H2O + acceptor
|
1.14.99.20
phylloquinone monooxygenase (2,3-epoxidizing)
|
–
|
|
|
BRENDA:
BR40389
KEGG:
R03510
MetaCyc:
1.14.99.20-RXN
|
|
|
|
vitamin_KH2 + a_protein_with_a_disulfide_bond <=> vitamin_K + a_protein_with_reduced_L-cysteine_residues
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
M
|
|
BRENDA:
BR52530
MetaCyc:
RXN-19672
|
|
|
|
NADPH + vitamin_K + H+ <=> NADP+ + vitamin_KH2
|
1.6.5.2
NAD(P)H dehydrogenase (quinone)
|
–
|
M
|
|
BRENDA:
BS370204
MetaCyc:
RXN-19671
|
|
|
|
NADH + vitamin_K + H+ <=> NAD+ + vitamin_KH2
|
1.6.5.2
NAD(P)H dehydrogenase (quinone)
7.1.1.2
NADH:ubiquinone reductase (H+-translocating)
|
–
–
|
K
|
|
BRENDA:
BS370204-a
KEGG:
R03643;
R03816
MetaCyc:
RXN-19671_WOP
|
|
|
|
vitamin_K + reduced_flavodoxin + O2 <=> omega-hydroxyphylloquinone + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
BRENDA:
BR51032
KEGG:
R10728
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + dithiothreitol <=> vitamin_K + oxidized_dithiothreitol
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
1.17.4.5
vitamin-K-epoxide reductase (warfarin-insensitive)
|
–
–
|
K
|
|
BRENDA:
BS188897
KEGG:
R03511
|
|
|
|
vitamin_K + oxidized_dithiothreitol + H2O <=> vitamin_K_epoxide + dithiothreitol
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
KEGG:
R03645
|
|
|
|
vitamin_K + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-hydroxyphylloquinone + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15395
|
|
|
|
vitamin_K + H2O <=> menadione + phytol
|
3.7.1
|
–
|
M
|
|
MetaCyc:
RXN-19670
|
|
|
|
vitamin_K + reduced_[NADPH-hemoprotein_reductase] + O2 <=> omega-carboxyphylloquinone + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.78
phylloquinone omega-hydroxylase
|
–
|
|
|
MetaCyc:
RXN-19684
|
|
|
|
N6-(2-isopentenyl)adenine + vitamin_K <=> adenine + 3-methylbut-2-enal + vitamin_KH2
|
1.5.99.12
cytokinin dehydrogenase
|
–
|
|
|
BRENDA:
BS373976
|
|
|
|
vitamin_K + electron_donor + O2 <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + oxidized_electron_donor + H2O
|
1.14.99.20
phylloquinone monooxygenase (2,3-epoxidizing)
|
–
|
|
|
BRENDA:
BS287933
|
|
|
|
vitamin_K + electron_donor + O2 <=> 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + oxidized_electron + H2O
|
1.14.99.20
phylloquinone monooxygenase (2,3-epoxidizing)
|
–
|
|
|
BRENDA:
BS370240
|
|
|
|
peptidyl-L-glutamate + CO2 + O2 + vitamin_K <=> peptidyl-4-carboxy_L-glutamate + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H2O
|
4.1.1.90
peptidyl-glutamate 4-carboxylase
|
–
|
|
|
BRENDA:
BS402835
|
|
|
|
S-adenosyl-L-methionine + demethylphylloquinone <=> S-adenosyl-L-homocysteine + vitamin_K
|
2.1.1.329
demethylphylloquinol methyltransferase
|
–
|
|
|
BRENDA:
BS438456
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + thioredoxin <=> vitamin_K + thioredoxin_disulfide
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS427885
|
|
|
|
vitamin_K + NADH <=> 2-methyl-3-phytyl-1,4-naphthohydroquinone + NAD+
|
1.6.5.2
NAD(P)H dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS260196-a
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + oxidized_dithiothreitol <=> vitamin_K + dithiothreitol
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS406877
|
|
|
|
vitamin_K + dithiothreitol <=> vitamin_KH2 + oxidized_dithiothreitol
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS387181
|
|
|
|
2,3-epoxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + dithiothreitol <=> vitamin_K + oxidized_dithiothreitol + H2O
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS442755
|
|
|
|
(S)-malate + vitamin_K <=> oxaloacetate + vitamin_KH2
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS403149
|
|
|
|
vitamin_K + NADPH <=> 2-methyl-3-phytyl-1,4-naphthohydroquinone + NADP+
|
1.6.5.2
NAD(P)H dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS260196
|
|